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Article | IMSEAR | ID: sea-217549

ABSTRACT

Background: Serum lactate levels are a direct quantification of gap in between energy-expenditure and oxidative capacity. Variation in the lactate levels among the resting individuals could be exigent, requiring attention often and raised lactate levels can be observed among the individuals with mitochondrial impairments in the oxidative phosphorylation pathways. Aim and Objectives: Aim and objectives of the study was to evaluate the association of serum lactate levels among Type 2 diabetes mellitus patients. Materials and Methods: This present observational cross-sectional study involved 300 diabetic patients who presented to the tertiary care hospital of Uttar Pradesh. The patients were stratified according to their random blood sugar, Glycated hemoglobin and lactate levels. Student t-test was used for assessing the significance, a probability of <0.05 is considered significant. Results: A total of 300 patients have been included in this study, of which 150 are males and 150 are females, the median age was 48 years. The highest age of patient included was 84 years, and the lowest of patient included in the study was 34 years. The patients with high lactate levels are found to have poor glycaemic control, which may further proceed to worst outcome of the disease. Conclusion: Serum lactate levels could be the potential predictor and reliable indicator of poor glycemic control/status of diabetic patients.

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